RESOURCES FOR MANAGING EPISODES OF FREQUENT SEIZURE ACTIVITY

Seizures can be difficult to manage, given their unpredictable nature. But along with VALTOCO® (diazepam nasal spray), you have resources that can help.

DOWNLOADABLE Resources

Feel free to save any or all of these documents to help you along your journey to managing seizures.

Doctor Discussion Guide

Doctor Discussion Guide

This can help you when it’s time to talk to your healthcare provider about VALTOCO.

Get the Guide

VALTOCO patient brochure

Patient Brochure

Get the guidance you need, including answers, tips, and resources, to help you carry VALTOCO with confidence.

Get the Brochure

VALTOCO instructions for use

Instructions for Use

Give this document to care partners, like friends, family, and coworkers, so that they know how to use VALTOCO to help treat your episodes of frequent seizure activity.

Get the Instructions

VALTOCO track your seizure clusters

Track Your Seizures

Documenting episodes of frequent seizure activity can help you better understand when and where they occur. Download the app from Seizure Tracker™.

VALTOCO tip sheet

Tip Sheet

If you've been prescribed VALTOCO through Maxor Specialty Pharmacy, follow these simple steps to ensure your prescription gets filled promptly.

Get the Tip Sheet

MATERIALES EN Español

Guarde estos documentos para ayudarle con su plan de respuesta a las convulsiones.

Guía del medicamento

Lee la información más importante que debe conocer sobre VALTOCO, incluyendo que es VALTOCO, como debes a utilizarlo, y más.

Descargarlo aquí

Instrucciones de uso:
dosis de 5 mg y 10 mg

Usted y sus familiares, cuidadores y otras personas que necesiten administrar VALTOCO deben leer estas instrucciones de uso que vienen con VALTOCO antes de usarlo.

Léelo aquí

Instrucciones de uso:
dosis de 15 mg y 20 mg

Usted y sus familiares, cuidadores y otras personas que necesiten administrar VALTOCO deben leer estas instrucciones de uso que vienen con VALTOCO antes de usarlo.

Léelo aquí

Folleto para pacientes

Esta es su guía de VALTOCO, con respuestas, consejos y recursos que lo ayudarán a ganar confianza.

Descarga el folleto aquí

Cómo obtener su recetado
de VALTOCO

Ayude a garantizar que reciba el VALTOCO que le recetaron si es a través de Maxor Specialty Pharmacy.

Descarga el documento aquí

VALTOCO ebook

THE PATH Toward PreparedA FREE EBOOK

This comprehensive guide is filled with tips, insights, and words of wisdom from people living with or caring for someone with epilepsy and frequent seizure episodes. From lifestyle tips to epilepsy education, The Path Toward Prepared is designed to help you or your loved ones prepare for frequent seizure episodes at home, school, work, or away.

This eBook is not intended to replace or provide any medical advice so make sure you talk to your healthcare provider before trying anything new.

Get the Guide

Patient Experiences

Patient Experiences

Maurene's epilepsy story thumbnail

Watch Maurene's Story

WATCH Maurenes Story
“VALTOCO gave me back the confidence
to go anywhere.”
- MAURENE, ADULT WITH SEIZURE
CLUSTERS

Watch more VALTOCO videos

Watch more VALTOCO videos
 
Request a VALTOCO prescription online today

Request a VALTOCO prescription from your healthcare provider online today

Request Prescription

VALTOCO now available in US retail pharmacies

Patients prescribed VALTOCO may pay as little as $20* with the VALTOCO Copay Card

Get Your Copay Card

Prescription Expiration Reminder

For your VALTOCO to work most effectively, make sure your on-hand rescue medication stays current. You can make sure you have fresh doses ready for you by identifying the expiration date of your VALTOCO.

VALTOCO bitmap

You can find the expiration date of your VALTOCO by looking at the VALTOCO box and blister pack.

VALTOCO bitmap

Set a Calendar Reminder

When Does Your Product Expire?

Please select an expiration month above.

Please select an expiration year above.

Please select an expiration month and year above.

Set A Reminder

It’s time to refill your VALTOCO prescription

For Google: Your calendar will pop up. Don’t forget to save it.

For iCal and Outlook: The file will download. Double-click it.

Savings and Support for VALTOCO

If eligible, you may pay as little as $20 with the VALTOCO copay card.

Find Out More

Online RESOURCES

There are communities and resources that champion the needs of those living with epilepsy and episodes of frequent seizure activity. Get familiar with them and, if it’s right for you, empower yourself by getting involved.

Epilepsy Foundation logo

EPILEPSY FOUNDATION

With a network of nearly 50 partners throughout the United States, the Epilepsy Foundation connects people to treatment, support, and resources. Visit epilepsy.com for more information.

Visit

National Institute of Neurological Disorders and Stroke (NINDS) logo

NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE (NINDS)

NINDS conducts and funds research on brain and nervous system disorders.

Visit

The NIH does not endorse or promote any particular products or services

Child Neurology Foundation logo

CHILDHOOD NEUROLOGY FOUNDATION (CNF)

CNF is a collaborative center of education and support for children and their families living with neurologic conditions.

Visit

Dravet Syndrome Foundation logo

DRAVET SYNDROME FOUNDATION (DSF)

DSF was founded by a group of parents with the purpose of supporting and funding research for Dravet syndrome and related epilepsies. The organization is committed to increasing awareness and providing support to affected individuals and families.

Visit

LGS Foundation logo

LGS FOUNDATION

The LGS Foundation's mission is to improve the lives of those affected by Lennox-Gastaut syndrome (LGS)—a rare epilepsy syndrome—through research, family support programs, and education.

Visit

CURE logo

CITIZENS UNITED FOR RESEARCH IN EPILEPSY (CURE)

CURE is a leading organization that is fully committed to finding a cure for epilepsy by promoting and funding patient-focused research.

Visit

EAA logo

EPILEPSY ALLIANCE AMERICA (EAA)

EAA is a new national organization dedicated to providing support, care, and services for people with epilepsy and their communities.

Visit

Tuberous Sclerosis Alliance logo

TUBEROUS SCLEROSIS (TS) ALLIANCE

The TS Alliance is dedicated to finding a cure for tuberous sclerosis complex, while improving the lives of those affected by this genetic disorder.

Visit

more information on seizure treatment

Get savings and support for VALTOCO and, if eligible, you may pay as little as $20 with the VALTOCO copay card.

IMPORTANT SAFETY INFORMATION,
INCLUDING BOXED WARNING

Down arrow

What is the most important information I should know about VALTOCO?

  • VALTOCO is a benzodiazepine medicine. Taking benzodiazepines with opioid medicines, alcohol, or other central nervous system (CNS) depressants (including street drugs) can cause severe drowsiness, breathing problems (respiratory depression), coma, and death. Get emergency help right away if any of the following happens:
    • Shallow or slowed breathing
    • Breathing stops (which may lead to the heart stopping)
    • Excessive sleepiness (sedation)
  • Risk of abuse, misuse, and addiction. There is a risk for abuse, misuse, and addiction with benzodiazepines, including VALTOCO, which can lead to overdose and serious side effects including coma and death.
    • Serious side effects have happened in people who have abused or misused benzodiazepines, including diazepam (the active ingredient in VALTOCO). These serious side effects may also include delirium, paranoia, suicidal thoughts or actions, seizures, and difficulty breathing. Call your healthcare provider or go to the nearest hospital emergency room right away if you get any of these serious side effects.
    • Use VALTOCO exactly as your healthcare provider prescribed.
  • Physical dependence and withdrawal reactions. Benzodiazepines, including VALTOCO, can cause physical dependence and withdrawal reactions, especially if you use VALTOCO daily. VALTOCO is not intended for daily use.
  • VALTOCO can make you sleepy or dizzy and can slow your thinking and motor skills.
    • Do not drive, operate heavy machinery, or do other dangerous activities until you know how VALTOCO affects you.
    • Do not drink alcohol or take opioid medicines that make you sleepy or dizzy while taking VALTOCO until you talk to your healthcare provider. When taken with alcohol or medicines that can cause sleepiness or dizziness, VALTOCO may make your sleepiness or dizziness worse.
  • Like other antiepileptic drugs, VALTOCO may cause suicidal thoughts or actions in a very small number of people, about 1 in 500. Call a healthcare provider right away if you have any new or worsening suicidal thoughts or related symptoms, especially unusual changes in mood, behaviors, thoughts or feelings.

How can I watch for early symptoms of suicidal thoughts or actions?

  • Pay attention to any changes, especially sudden changes in mood, behaviors, thoughts, or feelings.
  • Keep all follow-up visits with your healthcare provider as scheduled.
  • Call your healthcare provider between visits as needed, especially if you are worried about symptoms. Suicidal thoughts or actions can be caused by things other than medicines. If you have suicidal thoughts or actions, your healthcare provider may check for other causes.

Do not use VALTOCO if you:

  • Are allergic to diazepam.
  • Have an eye problem called acute narrow-angle glaucoma.

What should I tell my doctor before taking VALTOCO?

Before using VALTOCO, tell your healthcare provider about all of your medical conditions, including if you:

  • Have asthma, emphysema, bronchitis, chronic obstructive pulmonary disease, or other breathing problems.
  • Have a history of alcohol or drug abuse.
  • Have a history of depression, mood problems, or suicidal thoughts or behavior.
  • Have liver or kidney problems.
  • Are pregnant or plan to become pregnant. VALTOCO may harm your unborn baby.
  • Are breastfeeding or plan to breastfeed. VALTOCO passes into your breast milk and may harm your baby. Talk to your healthcare provider about the best way to feed your baby if you use VALTOCO.

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

How should I use VALTOCO?

  • Read the Instructions for Use for detailed information about the right way to use VALTOCO.
  • Use VALTOCO exactly as prescribed by the healthcare provider.
  • Your healthcare provider will tell you:
    • What seizure clusters are
    • Exactly how much VALTOCO to give
    • When and how to give VALTOCO
    • What to do after you give VALTOCO if the seizures do not stop or there is a change in breathing, behavior, or condition that worries you
  • You should carry VALTOCO with you in case you need to control your seizure clusters.
  • VALTOCO is given in the nose (nasal) only.
  • Each VALTOCO only sprays 1 time and cannot be reused. Do not test or prime the nasal spray before use.
  • Each dose of VALTOCO is provided in an individual pack. Use all of the medicine in 1 pack for a complete dose.

What should I do after I give VALTOCO?

  • Stay with the person after you give VALTOCO and watch them closely.
  • Make a note of the time VALTOCO was given.
  • Call for emergency help if any of the following happen:
    • Seizure cluster behavior is different than other seizure clusters the person has had.
    • You are alarmed by how often the seizures happen, by how severe the seizure is, by how long the seizure lasts, or by the color or breathing of the person.
  • Throw away (discard) the used VALTOCO.

If needed, a second dose may be given at least 4 hours after the first dose, using a new pack of VALTOCO. Do not give more than 2 doses of VALTOCO to treat a seizure cluster.

A second dose should not be given if there is concern about the person's breathing, they need help with their breathing, or have extreme drowsiness.

Do not use VALTOCO for more than 1 seizure cluster episode every 5 days. Do not use VALTOCO for more than 5 seizure cluster episodes in 1 month.

What are the most common side effects of VALTOCO?

The most common side effects of VALTOCO include:

  • Feeling sleepy or drowsy
  • Headache
  • Nose discomfort

These are not all of the possible side effects of VALTOCO. Call your healthcare provider for medical advice about side effects. You may report side effects to Neurelis, Inc. at 1-866-696-3873 or to FDA at 1-800-FDA-1088.

Please see full Prescribing Information and Medication Guide for additional important safety information.

What is VALTOCO® (diazepam nasal spray)?

  • VALTOCO is a prescription medicine used for the short-term treatment of seizure clusters (also known as “episodes of frequent seizure activity” or “acute repetitive seizures”) in patients 6 years of age and older.
  • VALTOCO is a federally controlled substance (CIV) because it can be abused or lead to dependence. Keep VALTOCO in a safe place to prevent misuse and abuse. Selling or giving away VALTOCO may harm others and is against the law. Tell your healthcare provider if you have abused or been dependent on alcohol, prescription drugs, or street drugs.
  • It is not known if VALTOCO is safe and effective in children under 6 years of age.

IMPORTANT SAFETY INFORMATION

What is the most important information I should know about VALTOCO?

  • VALTOCO is a benzodiazepine medicine. Taking benzodiazepines with opioid medicines, alcohol, or other central nervous system (CNS) depressants (including street drugs) can cause severe drowsiness, breathing problems (respiratory depression), coma, and death. Get emergency help right away if any of the following happens:
    • Shallow or slowed breathing
    • Breathing stops (which may lead to the heart stopping)
    • Excessive sleepiness (sedation)
  • Risk of abuse, misuse, and addiction. There is a risk for abuse, misuse, and addiction with benzodiazepines, including VALTOCO, which can lead to overdose and serious side effects including coma and death.
    • Serious side effects have happened in people who have abused or misused benzodiazepines, including diazepam (the active ingredient in VALTOCO). These serious side effects may also include delirium, paranoia, suicidal thoughts or actions, seizures, and difficulty breathing. Call your healthcare provider or go to the nearest hospital emergency room right away if you get any of these serious side effects.
    • Use VALTOCO exactly as your healthcare provider prescribed.
  • Physical dependence and withdrawal reactions. Benzodiazepines, including VALTOCO, can cause physical dependence and withdrawal reactions, especially if you use VALTOCO daily. VALTOCO is not intended for daily use.
  • VALTOCO can make you sleepy or dizzy and can slow your thinking and motor skills.
    • Do not drive, operate heavy machinery, or do other dangerous activities until you know how VALTOCO affects you.
    • Do not drink alcohol or take opioid medicines that make you sleepy or dizzy while taking VALTOCO until you talk to your healthcare provider. When taken with alcohol or medicines that can cause sleepiness or dizziness, VALTOCO may make your sleepiness or dizziness worse.
  • Like other antiepileptic drugs, VALTOCO may cause suicidal thoughts or actions in a very small number of people, about 1 in 500. Call a healthcare provider right away if you have any new or worsening suicidal thoughts or related symptoms, especially unusual changes in mood, behaviors, thoughts or feelings.

How can I watch for early symptoms of suicidal thoughts or actions?

  • Pay attention to any changes, especially sudden changes in mood, behaviors, thoughts, or feelings.
  • Keep all follow-up visits with your healthcare provider as scheduled.
  • Call your healthcare provider between visits as needed, especially if you are worried about symptoms. Suicidal thoughts or actions can be caused by things other than medicines. If you have suicidal thoughts or actions, your healthcare provider may check for other causes.

Do not use VALTOCO if you:

  • Are allergic to diazepam.
  • Have an eye problem called acute narrow-angle glaucoma.

What should I tell my doctor before taking VALTOCO?

Before using VALTOCO, tell your healthcare provider about all of your medical conditions, including if you:

  • Have asthma, emphysema, bronchitis, chronic obstructive pulmonary disease, or other breathing problems.
  • Have a history of alcohol or drug abuse.
  • Have a history of depression, mood problems, or suicidal thoughts or behavior.
  • Have liver or kidney problems.
  • Are pregnant or plan to become pregnant. VALTOCO may harm your unborn baby.
  • Are breastfeeding or plan to breastfeed. VALTOCO passes into your breast milk and may harm your baby. Talk to your healthcare provider about the best way to feed your baby if you use VALTOCO.

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

How should I use VALTOCO?

  • Read the Instructions for Use for detailed information about the right way to use VALTOCO.
  • Use VALTOCO exactly as prescribed by the healthcare provider.
  • Your healthcare provider will tell you:
    • What seizure clusters are
    • Exactly how much VALTOCO to give
    • When and how to give VALTOCO
    • What to do after you give VALTOCO if the seizures do not stop or there is a change in breathing, behavior, or condition that worries you
  • You should carry VALTOCO with you in case you need to control your seizure clusters.
  • VALTOCO is given in the nose (nasal) only.
  • Each VALTOCO only sprays 1 time and cannot be reused. Do not test or prime the nasal spray before use.
  • Each dose of VALTOCO is provided in an individual pack. Use all of the medicine in 1 pack for a complete dose.

What should I do after I give VALTOCO?

  • Stay with the person after you give VALTOCO and watch them closely.
  • Make a note of the time VALTOCO was given.
  • Call for emergency help if any of the following happen:
    • Seizure cluster behavior is different than other seizure clusters the person has had.
    • You are alarmed by how often the seizures happen, by how severe the seizure is, by how long the seizure lasts, or by the color or breathing of the person.
  • Throw away (discard) the used VALTOCO.

If needed, a second dose may be given at least 4 hours after the first dose, using a new pack of VALTOCO. Do not give more than 2 doses of VALTOCO to treat a seizure cluster.

A second dose should not be given if there is concern about the person's breathing, they need help with their breathing, or have extreme drowsiness.

Do not use VALTOCO for more than 1 seizure cluster episode every 5 days. Do not use VALTOCO for more than 5 seizure cluster episodes in 1 month.

What are the most common side effects of VALTOCO?

The most common side effects of VALTOCO include:

  • Feeling sleepy or drowsy
  • Headache
  • Nose discomfort

These are not all of the possible side effects of VALTOCO. Call your healthcare provider for medical advice about side effects. You may report side effects to Neurelis, Inc. at 1-866-696-3873 or to FDA at 1-800-FDA-1088.

Please see full Prescribing Information and Medication Guide for additional important safety information.

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